IN CATEGORY

$tax_query = array(
	'relation' => 'AND',
	array(
		'taxonomy'         => 'category',
		'terms'            => array( '1453', ' 1426', ' 1431', ' 1439', ' 1445' ),
		'field'            => 'term_taxonomy_id',
		'operator'         => 'NOT IN',
		'include_children' => true,
	),
	array(
		'taxonomy'         => 'themes',
		'terms'            => array( '111', '222', '333' ),
		'field'            => 'term_taxonomy_id',
		'operator'         => 'IN',
		'include_children' => true,
	),
	array(
		'taxonomy'         => 'category',
		'terms'            => array( '333', '444' ),
		'field'            => 'term_taxonomy_id',
		'operator'         => 'IN',
		'include_children' => true,
	),
);